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OCR: lig cells to LH interacts with receptors o ylate cyclase (Fig. d into the stimulate a membrane-boun 11.5). cAMP is subsequently in kinase. cytoplasm where it binds to a perating through Activation of the protein kir mulates the unidentified intermediate ste enolone. The conversion of cholesterol to negative oestradiol can control of LH operates prima feedback, and both testostero an be converted inhibit LH secretion. Testost vo hormones are to oestradiol in the brain, but H secretion, believed to act independentl ic pulse 1 thus decreases Testosterone slows the hypo se. It also exerts a generator in the hypothalam etion directly at the frequency of pulsatile LH negative feedback effect on L the pituitary level.